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1

Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study

Caicun Zhou, Yi-Long Wu, Gongyan Chen, Jifeng Feng, Xiao-Qing Liu, Changli Wang, Shucai Zhang, Jie Wang, Songwen Zhou, Shengxiang Ren, Shun Lu, Li Zhang, Chengping Hu, Chunhong Hu, Yi Luo, Lei Chen, M

Journal:

The Lancet Oncology

Year:

2011

Language:

english

File:

PDF, 265 KB

english, 2011

2

Consolidative Local Ablative Therapy Improves the Survival of Patients With Synchronous Oligometastatic NSCLC Harboring EGFR Activating Mutation Treated With First-Line EGFR-TKIs

Xu, Qinghua, Zhou, Fei, Liu, Hui, Jiang, Tao, Li, Xuefei, Xu, Yaping, Zhou, Caicun

Journal:

Journal of Thoracic Oncology

Year:

2018

Language:

english

File:

PDF, 1.24 MB

english, 2018

3

Mechanisms of drugs-resistance in small cell lung cancer: DNA-related, RNA-related, apoptosis-related, drug accumulation and metabolism procedure

Chen, Peixin, Kuang, Peng, Wang, Lei, Li, Wei, Chen, Bin, Liu, Yu, Wang, Hao, Zhao, Sha, Ye, Lingyun, Yu, Feng, He, Yayi, Zhou, Caicun

Journal:

Translational Lung Cancer Research

Year:

2020

File:

PDF, 499 KB

2020

4

miR-512-5p induces apoptosis and inhibits glycolysis by targeting p21 in non-small cell lung cancer cells

Chu, Kaili, Gao, Guanghui, Yang, Xiufang, Ren, Shengxiang, Li, Yao, Wu, Hai, Huang, Yan, Zhou, Caicun

Journal:

International Journal of Oncology

Year:

2015

Language:

english

File:

PDF, 955 KB

english, 2015

5

High Discrepancy of Driver Mutations in Patients with NSCLC and Synchronous Multiple Lung Ground-Glass Nodules

Wu, Chunyan, Zhao, Chao, Yang, Yang, He, Yayi, Hou, Likun, Li, Xuefei, Gao, Guanghui, Shi, Jingyun, Ren, Shengxiang, Chu, Haiqing, Zhou, Caicun, Zhang, Jun, Schmid-Bindert, Gerald

Journal:

Journal of Thoracic Oncology

Year:

2015

Language:

english

File:

PDF, 817 KB

english, 2015

6

A randomized, double-blind, phase III study comparing two doses of erlotinib for second-line treatment of current smokers with advanced non-small-cell lung cancer (CurrentS)

Smit, Egbert F., Wu, Yi-Long, Gervais, Radj, Zhou, Caicun, Felip, Enriqueta, Feng, Jifeng, Guclu, Salih Zeki, Hoiczyk, Mathias, Dorokhova, Elena, Freudensprung, Ulrich, Grange, Susan, Perez-Moreno, Pa

Journal:

Year:

2016

Language:

english

File:

PDF, 1.40 MB

english, 2016

7

SC05.03 Novel Tyrosine Kinase Inhibitors in Lung Cancer

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 124 KB

english, 2017

8

The tumor suppressor p53 regulates autophagosomal and lysosomal biogenesis in lung cancer cells by targeting transcription factor EB

Zhang, Zengli, Wang, Hongfeng, Ding, Qifeng, Xing, Yufei, Xu, Delai, Xu, Zhonghua, Zhou, Tong, Qian, Bin, Ji, Chenghong, Pan, Xue, Zhong, Anyuan, Ying, Zheng, Zhou, Caicun, Shi, Minhua

Journal:

Biomedicine & Pharmacotherapy

Year:

2017

Language:

english

File:

PDF, 1.46 MB

english, 2017

9

Combination Strategies on the Basis of Immune Checkpoint Inhibitors in Non-small-cell Lung Cancer: Where do we stand?

Qiao, Meng, Jiang, Tao, Ren, Shengxiang, Zhou, Caicun

Journal:

Clinical Lung Cancer

Year:

2017

Language:

english

File:

PDF, 920 KB

english, 2017

10

Icotinib versus whole-brain irradiation in patients with EGFR -mutant non-small-cell lung cancer and multiple brain metastases (BRAIN): a multicentre, phase 3, open-label, parallel, randomised controlled trial

Yang, Jin-Ji, Zhou, Caicun, Huang, Yisheng, Feng, Jifeng, Lu, Sun, Song, Yong, Huang, Cheng, Wu, Gang, Zhang, Li, Cheng, Ying, Hu, Chengping, Chen, Gongyan, Zhang, Li, Liu, Xiaoqing, Yan, Hong Hong, T

Journal:

The Lancet Respiratory Medicine

Year:

2017

Language:

english

File:

PDF, 536 KB

english, 2017

11

Predictive value of oncogenic driver subtype, programmed death‐1 ligand (PD‐L1) score, and smoking status on the efficacy of PD‐1/PD‐L1 inhibitors in patients with oncogene‐driven non–small cell lung cancer

Ng, Terry L., Liu, Yiwei, Dimou, Anastasios, Patil, Tejas, Aisner, Dara L., Dong, Zhengwei, Jiang, Tao, Su, Chunxia, Wu, Chunyan, Ren, Shengxiang, Zhou, Caicun, Camidge, D. Ross

Journal:

Year:

2018

Language:

english

File:

PDF, 846 KB

english, 2018

12

Dynamic Monitoring and Predictive Value of Circulating Tumor Cells in EGFR-Mutated Advanced Non–Small-Cell Lung Cancer Patients Treated With First-Line EGFR Tyrosine Kinase Inhibitors

Jiang, Tao, Zhao, Jing, Zhao, Chao, Li, Xuefei, Shen, Jiqiao, Zhou, Juan, Ren, Shengxiang, Su, Chunxia, Zhou, Caicun, O'Brien, Mary

Journal:

Clinical Lung Cancer

Year:

2018

Language:

english

File:

PDF, 1.59 MB

english, 2018

13

Nivolumab Versus Docetaxel in a Predominantly Chinese Patient Population With Previously Treated Advanced NSCLC: CheckMate 078 Randomized Phase III Clinical Trial

Wu, Yi-Long, Lu, Shun, Cheng, Ying, Zhou, Caicun, Wang, Jie, Mok, Tony, Zhang, Li, Tu, Hai-Yan, Wu, Lin, Feng, Jifeng, Zhang, Yiping, Luft, Alexander Valerievich, Zhou, Jianying, Ma, Zhiyong, Lu, You,

Journal:

Journal of Thoracic Oncology

Year:

2019

Language:

english

File:

PDF, 363 KB

english, 2019

14

CNS Response to Osimertinib Versus Standard Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Patients With Untreated EGFR -Mutated Advanced Non–Small-Cell Lung Cancer

Reungwetwattana, Thanyanan, Nakagawa, Kazuhiko, Cho, Byoung Chul, Cobo, Manuel, Cho, Eun Kyung, Bertolini, Alessandro, Bohnet, Sabine, Zhou, Caicun, Lee, Ki Hyeong, Nogami, Naoyuki, Okamoto, Isamu, Le

Journal:

Journal of Clinical Oncology

Year:

2018

File:

PDF, 711 KB

2018

15

Randomized Study of Individualized Pharmacokinetically‐Guided Dosing of Paclitaxel Compared with Body‐Surface Area Dosing in Chinese Patients with Advanced Non‐Small Cell Lung Cancer

Zhang, Jie, Zhou, Fei, Qi, Huiwei, Ni, Huijuan, Hu, Qiong, Zhou, Caicun, Li, Yunying, Baburina, Irina, Courtney, Jodi, Salamone, Salvatore J.

Journal:

British Journal of Clinical Pharmacology

Year:

2019

Language:

english

File:

PDF, 1.35 MB

english, 2019

16

Camrelizumab plus carboplatin and pemetrexed versus chemotherapy alone in chemotherapy-naive patients with advanced non-squamous non-small-cell lung cancer (CameL): a randomised, open-label, multicentre, phase 3 trial

Zhou, Caicun, Chen, Gongyan, Huang, Yunchao, Zhou, Jianying, Lin, LiZhu, Feng, Jifeng, Wang, Zhehai, Shu, Yongqian, Shi, Jianhua, Hu, Yi, Wang, QiMing, Cheng, Ying, Wu, Fengying, Chen, Jianhua, Lin, X

Journal:

The Lancet Respiratory Medicine

Year:

2020

File:

PDF, 1.24 MB

2020

17

Integrin beta1 over-expression associates with resistance to tyrosine kinase inhibitor gefitinib in non-small cell lung cancer

Lixia Ju, Caicun Zhou, Wei Li, Linghua Yan

Journal:

Journal of Cellular Biochemistry

Year:

2010

Language:

english

File:

PDF, 3.35 MB

english, 2010

18

Prediction of epidermal growth factor receptor mutations in the plasma/pleural effusion to efficacy of gefitinib treatment in advanced non-small cell lung cancer

Guo Jian, Zhou Songwen, Zhang Ling, Deng Qinfang, Zhang Jie, Tang Liang, Zhou Caicun

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2010

Language:

english

File:

PDF, 354 KB

english, 2010

19

Analysis of the clinical characteristics between cavitating squamous cell lung carcinoma and non-cavitating squamous cell lung carcinoma

Aiwu Li, Caicun Zhou, Jianfang Xu, Jian Ni, Jie Zhang, Jingyun Shi, Jie Luo

Journal:

The Chinese-German Journal of Clinical Oncology

Year:

2007

Language:

english

File:

PDF, 245 KB

english, 2007

20

Expression of Collagen IV, Fibronectin, Laminin in Non-small Cell Lung Cancer and Its Correlation with Chemosensitivities and Apoptosis

Yan XU, Yinmin ZHAO, Bo SU, Ying CHEN, Caicun ZHOU

Journal:

The Chinese-German Journal of Clinical Oncology

Year:

2006

Language:

english

File:

PDF, 253 KB

english, 2006

21

Immunotherapy of EGFR-positive tumor based on recombinant EGFR phage vaccine

Dong Liu, Liang Tang, Caicun Zhou, Lisong Tan

Journal:

The Chinese-German Journal of Clinical Oncology

Year:

2006

Language:

english

File:

PDF, 214 KB

english, 2006

22

Influence of comorbidity on the choice of treatment and survival of elderly patients with advanced non-small cell lung cancer

Aiwu Li, Caicun Zhou, Jianfang Xu, Ren Zhu, Jie Luo, Shanhao Chen

Journal:

The Chinese-German Journal of Clinical Oncology

Year:

2008

Language:

english

File:

PDF, 94 KB

english, 2008

23

Combination chemotherapy with irinotecan and cisplatin as second-line treatment for small cell lung cancer

Jie Luo, Ying Xu, Songwen Zhou, Aiwu Li, Di Zheng, Jianfang Xu, Caicun Zhou

Journal:

The Chinese-German Journal of Clinical Oncology

Year:

2008

Language:

english

File:

PDF, 278 KB

english, 2008

24

Gefitinib in the treatment of 41 cases with refractory non-small cell lung cancer

Jianfang Xu, Caicun Zhou, Aiwu Li

Journal:

The Chinese-German Journal of Clinical Oncology

Year:

2009

Language:

english

File:

PDF, 76 KB

english, 2009

25

BIM induction of apoptosis triggered by EGFR-sensitive and resistance cell lines of non-small-cell lung cancer

Zhanxia Li, Songwen Zhou, Ling Zhang, Chunxia Su, Jinqin Hang, Yinmin Zhao, Bo Su, Caicun Zhou

Journal:

Medical Oncology

Year:

2011

Language:

english

File:

PDF, 293 KB

english, 2011

26

ERCC1, RRM1 and BRCA1 mRNA expression levels and clinical outcome of advanced non-small cell lung cancer

Chunxia Su, Songwen Zhou, Ling Zhang, Shengxiang Ren, Jianfang Xu, Jie Zhang, Meijun Lv, Jie Zhang, Caicun Zhou

Journal:

Medical Oncology

Year:

2011

Language:

english

File:

PDF, 277 KB

english, 2011

27

Integrin-targeted paclitaxel nanoliposomes for tumor therapy

Shuyan Meng, Bo Su, Wei Li, Yongmei Ding, Liang Tang, Wei Zhou, Yin Song, Zhou Caicun

Journal:

Medical Oncology

Year:

2011

Language:

english

File:

PDF, 541 KB

english, 2011

28

Serum cytokine levels in patients with advanced non-small cell lung cancer: correlation with treatment response and survival

Chunxia Su, Caicun Zhou, Songwen Zhou, Jianfang Xu

Journal:

Medical Oncology

Year:

2011

Language:

english

File:

PDF, 171 KB

english, 2011

29

Clinical efficacy of erlotinib in patients previously treated for advanced non-small cell lung cancer

Songwen ZHOU, Shengxiang REN, Lianghua YAN, Ling ZHANG, Liang TANG, Jie ZHANG, Caicun ZHOU

Journal:

Year:

2009

Language:

english

File:

PDF, 496 KB

english, 2009

30

Enhanced antitumor effect of novel dual-targeted paclitaxel liposomes

Meng, Shuyan, Su, Bo, Li, Wei, Ding, Yongmei, Tang, Liang, Zhou, Wei, Song, Yin, Li, Heyan, Zhou, Caicun

Journal:

Year:

2010

Language:

english

File:

PDF, 330 KB

english, 2010

31

Association of EGFR mutation or ALK rearrangement with expression of DNA repair and synthesis genes in never-smoker women with pulmonary adenocarcinoma

Shengxiang Ren, Xiaoxia Chen, Peng Kuang, Limou Zheng, Chunxia Su, Jiayu Li, Bing Li, Yongshen Wang, Lu Liu, Qiong Hu, Jie Zhang, Liang Tang, Xuefei Li, Caicun Zhou, Gerald Schmid-Bindert

Journal:

Year:

2012

Language:

english

File:

PDF, 842 KB

english, 2012

32

Epidermal growth factor receptor-tyrosine kinase inhibitor therapy is effective as first-line treatment of advanced non-small-cell lung cancer with mutated EGFR: A meta-analysis from six phase III randomized controlled trials

Guanghui Gao, Shengxiang Ren, Aiwu Li, Jianfang Xu, Qinghua Xu, Chunxia Su, Jian Guo, Qinfang Deng, Caicun Zhou

Journal:

International Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 1.19 MB

english, 2012

33

Association of XRCC3 and XPD751 SNP with efficacy of platinum-based chemotherapy in advanced NSCLC patients

Xiaoxia Chen, Hui Sun, Shengxiang Ren, Vikramsingh Kim Curran, Ling Zhang, Songwen Zhou, Jie Zhang, Caicun Zhou

Journal:

Clinical and Translational Oncology

Year:

2012

Language:

english

File:

PDF, 408 KB

english, 2012

34

Prognostic factors for survival in a Chinese population presenting with advanced non-small cell lung cancer with an emphasis on smoking status: A regional, single-institution, retrospective analysis of 4552 patients

Qiong Hu, Bing Li, David Garfield, Shengxiang Ren, Aiwu Li, Xiaoxia Chen, CaiCun Zhou

Journal:

Thoracic Cancer

Year:

2012

Language:

english

File:

PDF, 751 KB

english, 2012

35

The association between polymorphisms in the DNA nucleotide excision repair genes and RRM1 gene and lung cancer risk

Xuefei Li, Jie Zhang, Chunxia Su, Xinping Zhao, Liang Tang, Caicun Zhou

Journal:

Thoracic Cancer

Year:

2012

Language:

english

File:

PDF, 98 KB

english, 2012

36

Predictive effects of RRM1, ERCC1, XRCC3, BRCA1 and EGFR genotyping or expression for clinical outcome of advanced NSCLC patients treated with cisplatin–based chemotherapy or gefitinib

Caicun Zhou, et al.

Journal:

Biomedicine & Pharmacotherapy

Year:

2009

Language:

english

File:

PDF, 115 KB

english, 2009

37

RGD-targeted paramagnetic liposomes for early detection of tumor: In vitro and in vivo studies

Wei Li, Bo Su, Shuyan Meng, Lixia Ju, Linghua Yan, Yongmei Ding, Yin Song, Wei Zhou, Heyan Li, Liang Tang, Yinmin Zhao, Caicun Zhou

Journal:

European Journal of Radiology

Year:

2011

Language:

english

File:

PDF, 918 KB

english, 2011

38

Vandetanib plus docetaxel versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer (ZODIAC): a double-blind, randomised, phase 3 trial

Roy S Herbst, Yan Sun, Wilfried EE Eberhardt, Paul Germonpré, Nagahiro Saijo, Caicun Zhou, Jie Wang, Longyun Li, Fairooz Kabbinavar, Yukito Ichinose, Shukui Qin, Li Zhang, Bonne Biesma, John V Heymach

Journal:

The Lancet Oncology

Year:

2010

Language:

english

File:

PDF, 327 KB

english, 2010

39

Safety and efficacy of first-line bevacizumab-based therapy in advanced non-squamous non-small-cell lung cancer (SAiL, MO19390): a phase 4 study

Lucio Crinò, Eric Dansin, Pilar Garrido, Frank Griesinger, Janessa Laskin, Nick Pavlakis, Daniel Stroiakovski, Nick Thatcher, Chun-Ming Tsai, Yi-long Wu, Caicun Zhou

Journal:

The Lancet Oncology

Year:

2010

Language:

english

File:

PDF, 204 KB

english, 2010

40

Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/3 randomised trial

Vincent A Miller, Vera Hirsh, Jacques Cadranel, Yuh-Min Chen, Keunchil Park, Sang-We Kim, Caicun Zhou, Wu-Chou Su, Mengzhao Wang, Yan Sun, Dae Seog Heo, Lucio Crino, Eng-Huat Tan, Tsu-Yi Chao, Mehdi S

Journal:

The Lancet Oncology

Year:

2012

Language:

english

File:

PDF, 373 KB

english, 2012

41

Gefitinib versus placebo as maintenance therapy in patients with locally advanced or metastatic non-small-cell lung cancer (INFORM; C-TONG 0804): a multicentre, double-blind randomised phase 3 trial

Li Zhang, Shenglin Ma, Xiangqun Song, Baohui Han, Ying Cheng, Cheng Huang, Shujun Yang, Xiaoqing Liu, Yunpeng Liu, Shun Lu, Jie Wang, Shucai Zhang, Caicun Zhou, Xiangwei Zhang, Nobuya Hayashi, Mengzha

Journal:

The Lancet Oncology

Year:

2012

Language:

english

File:

PDF, 371 KB

english, 2012

42

Predicting malignancy in mediastinal lymph nodes by endobronchial ultrasound: A new ultrasound scoring system

SCHMID-BINDERT, GERALD, JIANG, HONGBIN, KÄHLER, GEORG, SAUR, JOACHIM, HENZLER, THOMAS, WANG, HAO, REN, SHENGXIANG, ZHOU, CAICUN, PILZ, LOTHAR R.

Journal:

Year:

2012

Language:

english

File:

PDF, 550 KB

english, 2012

43

KIF5B-RET fusions in Chinese patients with non-small cell lung cancer

Cai, Weijing, Su, Chunxia, Li, Xuefei, Fan, Lihong, Zheng, Limou, Fei, Ke, Zhou, Caicun

Journal:

Year:

2013

Language:

english

File:

PDF, 742 KB

english, 2013

44

Analysis of Driver Mutations in Female Non-Smoker Asian Patients with Pulmonary Adenocarcinoma

Shengxiang Ren, Peng Kuang, Limou Zheng, Chunxia Su, Jiayu Li, Bing Li, Xiaoxia Chen, Yongshen Wang, V. KimCurran, Lu Liu, Qiong Hu, Jie Zhang, Liang Tang, Caicun Zhou

Journal:

Cell Biochemistry and Biophysics

Year:

2012

Language:

english

File:

PDF, 239 KB

english, 2012

45

Association between polymorphisms of DNA repair genes and survival of advanced NSCLC patients treated with platinum-based chemotherapy

Ren, Shengxiang, Zhou, Songwen, Wu, Fengyin, Zhang, Ling, Li, Xuefei, Zhang, Jie, Xu, Jianfang, Lv, Meijun, Zhang, Jie, Zhou, Caicun

Journal:

Year:

2012

Language:

english

File:

PDF, 306 KB

english, 2012

46

Proteomics-based identification of secreted protein dihydrodiol dehydrogenase 2 as a potential biomarker for predicting cisplatin efficacy in advanced NSCLC patients

Kuang, Peng, Zhou, Caicun, Li, Xuefei, Ren, Shengxiang, Li, Bing, Wang, Yongsheng, Li, Jiayu, Tang, Liang, Zhang, Jie, Zhao, Yinmin

Journal:

Year:

2012

Language:

english

File:

PDF, 445 KB

english, 2012

47

β-Catenin overexpression is associated with gefitinib resistance in non-small cell lung cancer cells

Fang, Xia, Gu, Pan, Zhou, Caicun, Liang, Aibin, Ren, Shenxiang, Liu, Fang, Zeng, Yu, Wu, Yunjin, Zhao, Yinmin, Huang, Binbin, Zhang, Zongmei, Yi, Xianghua

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.69 MB

english, 2014

48

Gefitinib-Resistance Is Related to BIM Expression in Non-Small Cell Lung Cancer Cell Lines

Li, Heyan, Zhou, Songwen, Li, Xuefei, Wang, Daoyuan, Wang, Yongsheng, Zhou, Caicun, Schmid-Bindert, Gerald

Journal:

Cancer Biotherapy & Radiopharmaceuticals

Year:

2013

Language:

english

File:

PDF, 769 KB

english, 2013

49

Association of integrin beta1 and c-MET in mediating EGFR TKI gefitinib resistance in non-small cell lung cancer

Lixia Ju, Caicun Zhou

Journal:

Cancer Cell International

Year:

2013

Language:

english

File:

PDF, 714 KB

english, 2013

50

A Case Report of Chemo-sensitive Intimal Pulmonary Artery Sarcoma

Xiaoxia Chen, Shengxiang Ren, Aiwu Li, Caicun Zhou

Journal:

Cell Biochemistry and Biophysics

Year:

2014

Language:

english

File:

PDF, 341 KB

english, 2014

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